Groundbreaking eye disease treatment trials to begin
cells derived from human embryonic stem cells for use in an attempt to slow, halt or reverse the effects of macular degeneration and dystrophy
A group of patients with eye disease common, incurable but that can lead to blindness must be injected cells in their eyes when two pioneering trials of a therapy that could cure the harm caused by the conditions.
Doctors have developed plans to address the first of the 24 patients were enrolled in the trials, from July, at the Jules Stein Eye Institute, University of California at Los Angeles.
medical teams expectslow, stop or even reverse the effects of the disease by injecting cells in the retina of the eye. . The treatment is controversial because the replacement of cells of the retina -. Known as the EPR, or cells of the retinal pigment epithelium-derived human embryonic stem cells
The announcement of these tests is a reference to cell technology company in the Massachusetts-based Advanced, which has been the development of therapy for 10 years.
In one trial, treatment should be given to ten patients with dry eye disorder called macular degeneration age-related dry (dry AMD). The second trial will focus on the same number of patients the disease called Stargardt's macular dystrophy, which usually strikes young people, aged 10 to 20.
early phase trials will focus on the safety of the therapy, which will be evaluated by doctors over 12 months. Patients in each trial was divided into four groups of three, each group receiving a different number of cells in the treatment.
- Steven Schwartz, chief of the division of the retina at the institute, said the test marked an important step toward addressing what was "an important medical needs of our time - for treatment form otherwise incurable blindness and common law. "
- dry macular degeneration is the most common cause of blindness in the developed world and the leading cause of vision loss in people over 55 years. As the population ages over the next 20 years, cases of dry AMD is expected to double.
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