Saturday, August 24, 2013

Could the 'triple whammy' technique that beat HIV/Aids win battle against cancer?

new gene therapies that attack tumors in multiple fronts can prolong life - but also showing more complex cancer cells that scientists had thought

Wing Commander Brian Liversidge was 60 in 2004 when she was diagnosed with aggressive prostate cancer. The president of an educational partnership Cumbria received 18 months.

Liversidge - who is married with two children and three grandchildren - mistook this gloomy prediction by a series of remarkable medical advances that have kept alive and raise the hope that will soon be possible to treat many cancers such as chronic and manageable.

However, history also reveals the considerable challenges ahead for scientists in their efforts to achieve this goal.

five different forms of treatment have been used - so far - to keep Liversidge life. He now lives in Colchester in Essex with his wife Susan, who remembers the battle he fought to prevent a cancer that has spread to his bones.

"There are side effects with all medications you take and it is sometimes difficult to distinguish the symptoms of cancer. Sometimes I felt so bad that I asked to be removed from treatment. But as. parent of the children, I am interested in advancing the treatment of prostate cancer as much as possible I like to hear the doctors say they have broken, "Liversidge said I really wanted to record their appreciation for the oncology teams - in Preston, Colchester and Marsden - who took care of him

The key development that has transformed the scientific strategy for the fight against cancer was the recent discovery that tumors are much more genetically complex than previously thought. "By analyzing tissue samples from cancer patients found that there is a huge genetic differences between cells in a tumor," said Professor Martin Gore of the Royal Marsden Hospital in London. "It was a surprise . "

Chris Jones, Institute of Cancer Research (ICR) in London, agreed. "Until recently, it was assumed cancerous cell clones were more or less identical. 'Ve found that this is not true. Cells derived from a single tumor of a person may have different genetic alterations within them. This presents a huge challenge in trying to develop treatments, but in the long term of our new consciousness should also provide the opportunity to create powerful anticancer drug plans. "

For most of the past 40 years, cancer has been treated with surgery, radiotherapy or chemotherapy. The latter technique involves the use of cytotoxic drugs that can kill cells that are. By carefully adjusting the doses of these drugs, doctors were able to kill cancer cells while sparing normal cells affected - in many cases. However, the high toxicity of chemotherapy drugs means that you can only manage a few weeks, which limits its ability to destroy tumors.


"Even if the cancer has spread through the body of a patient, melt tumors," said Workman. "Patients feel good. Seemed cancer drug perfect. Recently Found not this effect is only temporary. After six months or more, the tumors become and when they do, are totally resistant to vemurafenib. "

And this is not an isolated case history. "We have seen that the resistance to appear with almost every one of the new generation of targeted cancer drugs have created," said Workman. "The drugs that work well in the beginning. Then the cancer from coming back in a way that does not respond to the drug. "

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Monday, August 12, 2013

Anyone for a stem-cell burger?

At the opening of the first hamburger grown in the laboratory in the world, the crucial question is: What do you know

It felt more like a carefully choreographed TV a news conference. But while we were in the cave, studying political soil for weeks before, had been the place of registration for the BBC2 program The Apprentice - You're fired

Monday the stage was decorated like Ready Steady Cook - gold picture with a wooden tray to the left of the stage and chairs arranged around a dining area to the right in a context of dance background purple and yellow lights. Oversized studio cameras and projectors banks were trained hard on the table, so it seemed quite normal when a real television presenter, came on stage to take over what was apparently a scientific conference.

With most dramatic delivery and assured that any regular scientific chair would probably gathered, ITV presenter Nina Hossain told the audience that they were there to attend the first in the world. "This is the first time that a hamburger made with cultured meat is cooked and tested. Please do not hesitate to tweet about the event. "

The first guest on stage was the scientist whose team designed and built the burger grown from muscle stem cells in the laboratory, after more than five years of research. Postmark physiologist at the University of Maastricht, said he had been transferred to the € 250,000 (€ 217,000) Patty after thinking about the environmental impact of the crash - the pollution and contribute to Climate Change - Global production of meat. And with the increase in population and demand for meat, these impacts will worsen. His godfather, Google co-founder Sergey Brin, shared his concerns, he said.

Moments after the announcement

unveiled his precious burger assembled audience - they were too far away to see properly - a chef, food writer and nutritionist were welcomed on stage, accompanied by waves of applause.

Hossain explained that because of the cost of the burger and the fact that there was so little of it, only those who have a taste on stage.

Post said his next goal was to improve the efficiency of the process of cell growth and improve the taste by adding fat cells.

thick is expected to create more "cuts" of meat, including meat, even if it requires more knowledge of tissue engineering, namely the ability to grow channels - much like blood vessels - which can eat meat center increasing nutrients and water. Similar technology has already been shown to work for medical applications.


message repeatedly asked two types of questions. The first: What other meat animals can be grown this way? The answer was nothing. A reporter asked if that included Penguin lion burgers or meat. "I hate the smell of penguins, but I think we can," said Post. "It can be done with any type of satellite [stem] cell of an animal." Message Hossain said he did not exclude lion make a hamburger.

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Tuesday, August 6, 2013

Could mindfulness help teachers manage stress?

Amanda Bailey

explains how mindfulness skills taught in school to help staff and students deal with stress and improve concentration

In recent years, I suffered a map smoothly through the development of a practical personal attention. I did not realize the impact at first, but now I can see the positive effects of care in my daily life

Mindfulness helped me to form my "monkey mind", which is how I describe a mind buzzing in all directions, without focusing on what really needs attention. Mindfulness, c ' is when we are aware of and focused on what we do. Now I can see my thoughts, and most of the time anyway, and find that they are much less likely to take over and consume me . Now I teach my skills to full consciousness for school students and support staff in the management of all the stress of everyday life at school more productively.

find this skill useful, spend less time rehashing the same problem. Now I can go back, spend the mental gears to a more stable world and, like magic, creativity and the ability to find solutions to performance problems. I am less reactive to stress and anxiety, which means that I think the result and not only at launch and regretting something you say or do later date. This is especially useful in education.

sleep better and seems to live on less calmer more alert autopilot feel, and worry less about what happened yesterday and what could go wrong tomorrow. All this for 20 to 40 minutes aside for taking the time to just stop and pause my day.

There

about three years, I found vigilance in schools. This non-profit initiative, has developed a program of eight weeks the attention of the school of your call. "B", which means "to stop, breathe and be. "I convinced my principal to allow me to attend some form of education. Course B.

last year, I had the chance to teach the program for sixth graders and execute test sessions in other age groups. I also met with staff training and, due to demand, during full self-consciousness through our popular multi-academy trust.

due to the incredible response from our students and staff and some positive results of the initial survey, there are now new members of staff trained to teach the course attention and is part of the curriculum. Across The Bright Futures Trust, courses teaching full consciousness are part of our offer to all employees in order to promote well-being. We have an excellent compensation and interest from a number of schools and colleges in the Northwest. I drove carefully through a number of schools where children may not normally have access to these opportunities.

adult

The course focuses on a series of mindfulness skills, others have two minutes to 30 minutes. This is not therapy, but provides the skills necessary to give staff a sample of care that can be used immediately. For three weeks, everyone wonders why it was not discovered these simple processing techniques and life years earlier.


conscious activity can be part of your daily life and try to be very careful what you do, if we run through one activity to another and live a life of unconsciously. For example, I try to brush my teeth and focus on the present instead of being brushed in my autopilot usual. This allows just recognize me when I'm pretty obsessed with what happens during the day. You can apply it to take a shower, walk the dog, driving or any other activity that approach tends to neglect.

Eating is another daily activity can be done automatically, but if we delay this and focus on the physical sensations to really eat, so we can enjoy what we eat and the awakening of our automatic and really enjoy and appreciate our food.


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